Mesothelioma Statistics

02. Survival Statistics

Mesothelioma Survival Statistics

Mesothelioma survival statistics can be reported as life expectancy (months or years) or survival rate (percentage of patients alive at a certain time).

• Mesothelioma life expectancy: The life expectancy for pleural mesothelioma is 18 months. For peritoneal mesothelioma it is 31 months. These life expectancies apply to patients undergoing some form of treatment.
• Mesothelioma survival rate: The 3-year survival rate with treatment for pleural mesothelioma is 23% and the same rate for peritoneal mesothelioma is 74%.

Mesothelioma survival may vary based on several factors. These include the type and stage of mesothelioma. These factors can influence which treatments are likely to benefit a patient. Treatment is the best way to improve survival.

Factors that impact mesothelioma survival include:

• Age
• Gender
• Mesothelioma stage at the time of diagnosis
• Mesothelioma type
• Overall health
• Treatment approach

A doctor may discuss certain statistics when talking about a patient’s mesothelioma prognosis. Prognosis is an estimate of a patient’s overall disease outlook, which includes life expectancy and survival.

Survival Rates by Mesothelioma Type

Mesothelioma location can influence survival. Pleural mesothelioma is by far the most common type of mesothelioma. While some survival statistics may seem discouraging, mesothelioma survival rates have been improving.

• Pleural mesothelioma has a 1-year survival rate of about 73% and a 5-year survival rate of about 12%.
• Peritoneal mesothelioma has a 1-year survival rate of about 92% and a 5-year survival rate of about 65%.
• Pericardial mesothelioma has a 1-year survival rate of about 26% and a 5-year survival rate of about 9%.
• Testicular mesothelioma has limited data available on survival, but research indicates a 5-year survival rate of about 58%.

Recent advancements in treatments may help patients feel more hopeful about these statistics. Promising treatments, like immunotherapy, are helping to improve prognosis even for complex cases.

Survival Rates by Mesothelioma Stage

Another factor influencing survival is mesothelioma stage. Stage indicates how far the cancer has progressed. Those diagnosed at early stages often experience more favorable survival rates than those diagnosed in later stages of mesothelioma. These rates are largely due to cancer progression and the type of treatment options often available.

Malignant pleural mesothelioma is the most common form of the cancer. As a result, it is the most studied form of the disease.

Pleural mesothelioma is the only type with an established staging system of its own. Other types, such as pericardial mesothelioma, are so rare that they do not have their own designated staging system. Despite this, doctors with experience treating rare types of mesothelioma may still help increase patients’ quality of life and survival with individualized treatment plans.

Survival Rates by Age and Gender

Certain demographic factors may also impact survival. Research shows age at diagnosis, biological sex and gender may impact survival rates. For example, female mesothelioma patients generally have better survival rates than men.

5-year Mesothelioma Survival Rates by Age and Sex*
Age at Diagnosis	Male	Female
<45	32%	53%
45 – 54	18%	32%
55 – 64	13%	18%
65 – 74	7%	16%
75+	4%	7%

_{*Includes individuals who did and did not receive treatment}

Data shows younger patients typically have better survival rates than older patients. This may be because younger patients tend to have better overall health and are often able to receive more aggressive mesothelioma treatments.

Mesothelioma Death Rate

Mesothelioma death rate refers to the rate of deaths caused by mesothelioma in a given time period. These statistics may also be referred to as mortality. The Centers for Disease Control and Prevention (CDC) reports:

• 54,905 people died in the United States from mesothelioma from 1999 to 2020
• ~2,500 mesothelioma deaths annually

Treatment may help patients extend life expectancy. Some long-term mesothelioma survivors have even lived for more than 15 years after their diagnosis.

Mesothelioma Death Rate by State

Mesothelioma death rate describes the rate of mesothelioma deaths per one million people. Mesothelioma death rates may vary by state. Differences could be due to increased levels of asbestos use and exposure in some states.

Mesothelioma Deaths by State 1999 - 2020

List of Mesothelioma Deaths by State

State	Deaths	Rate per One Million
Alabama	668	6
Alaska	111	7
Arizona	1,077	8
Arkansas	357	6
California	5,484	7
Colorado	674	6
Connecticut	751	10
Delaware	239	12
District of Columbia	41	3
Florida	3,676	9
Georgia	856	4
Hawaii	154	5
Idaho	304	9
Illinois	2,490	9
Indiana	1,213	9
Iowa	560	8
Kansas	426	7
Kentucky	629	7
Louisiana	1,016	10
Maine	490	17
Maryland	976	8
Massachusetts	1,642	11
Michigan	2,068	9
Minnesota	1,285	11
Mississippi	378	6
Missouri	976	7
Montana	256	12
Nebraska	316	8
Nevada	383	7
New Hampshire	301	10
New Jersey	2,129	11
New Mexico	294	7
New York	2,981	7
North Carolina	1,266	6
North Dakota	153	10
Ohio	2,505	10
Oklahoma	530	6
Oregon	927	11
Pennsylvania	3,488	13
Rhode Island	256	11
South Carolina	743	7
South Dakota	130	7
Tennessee	960	7
Texas	2,900	5
Utah	335	6
Vermont	124	9
Virginia	1,598	9
Washington	1,717	12
West Virginia	530	13
Wisconsin	1,410	11
Wyoming	132	11
	Total: 54,905	Average: 8

03. Treatment Facts

Mesothelioma Treatment Facts

Mesothelioma treatment is the best way to extend patient survival and improve quality of life. A treatment’s impact on survival will vary depending on the individual. Patients who outlive their prognoses have usually undergone multimodal treatment. Multimodal treatment is when doctors use two or more treatment methods. Some mesothelioma doctors consider multimodal treatment the best chance for a cure.

• Standard mesothelioma treatments include chemotherapy, immunotherapy, radiation and surgery.
• Patients with early-stage mesothelioma are often treated with aggressive techniques, like surgery. Some patients in the later stages of disease may still be eligible for these treatments.
• Chemotherapy may be used in combination with surgical options to decrease the risk of recurring cancer. Chemotherapy statistics show the treatment has extended survival when used with other treatments.
• Mesothelioma patients who do not undergo any form of treatment generally survive about six months following diagnosis.

Clinical trials may be an option for mesothelioma patients to try new treatment methods and combinations. Participation in trials may also help cut down on treatment costs and extend survival.

In a 2020 study, pleural mesothelioma patients received multiple treatments. Chemotherapy came first, then pleurectomy and decortication (P/D) surgery. Some patients also received additional chemotherapy after surgery. The study reported a few encouraging results:

• Median survival: ~5 years
• 1-year survival rate: 93%
• 3-year survival rate: 65%

Multimodal therapy has also helped peritoneal mesothelioma patients. One study combined surgery with heated intraperitoneal chemotherapy (HIPEC). Patients also received another type of chemotherapy. This approach had a positive impact on prognosis. The study reported:

• A median survival of 5.4 years
• A 5-year survival rate of 52%

Another recent study combined two forms of immunotherapy. Pleural mesothelioma patients received CAR T-cell therapy and Keytruda®. These patients had a median survival of about 24 months (2 years).

Treatment Costs and Assistance Options

Cancer treatment can be costly. For mesothelioma, treatment costs will vary greatly depending upon a patient’s treatment plan. In general, patients can expect costs associated with diagnosis, treatment procedures, quality of life care and ongoing checkups. These costs may seem overwhelming, but there are options for families to help cover these expenses.

• Diagnosis: The only definitive way to diagnose mesothelioma is through testing a biopsy sample. In one study, a thoracoscopic pleural biopsy cost $16,575 on average.
• Treatment: Treatment plans vary based on a patient’s mesothelioma type, stage and overall health. Some plans may include surgery and chemotherapy. For example, patients may receive a P/D surgery, which costs $53,993 on average for mesothelioma. Surgery may be accompanied by chemotherapy, such as the combination of Alimta® (pemetrexed) and cisplatin. For an average male patient in 2017, the recommended dosage cost $38,779.
• Symptom care: Patients may receive other treatments to alleviate symptoms and improve quality of life. One such procedure is drainage of the pleural cavity, which can relieve pleural effusions. A recent study reported this cost on average to be $16,089.
• Other costs: Patients and their loved ones may also need to factor in other costs. These could include travel to treatment facilities, follow up treatments and end-of-life care.

Patients and loved ones can prepare for these costs in various ways. Savings, insurance and financial assistance may all be helpful.

Financial assistance may come in many forms. For example, mesothelioma patients may be eligible for compensation from parties responsible for their asbestos exposure. Asbestos disease compensation options include bankruptcy trust claims, settlements and lawsuit verdicts.

Veterans with mesothelioma may also be eligible for monthly VA benefits.

Mesothelioma patients and their loved ones can take advantage of these options to help pay for mesothelioma treatment and care.

04. Mesothelioma Risk Factors

Who Gets Mesothelioma?

Any person exposed to asbestos is at risk of developing mesothelioma. There is no safe level of asbestos exposure. A number of risk factors can influence an individual’s likelihood of developing an asbestos disease, including long periods of exposure and age.

Mesothelioma statistics also show the disease is more commonly diagnosed in male patients, Caucasians and people who are 65 years old and older. It is rarer in women and people under 45 years of age.

Latency Period Facts

Mesothelioma cancer has a long latency period. This refers to the length of time between asbestos exposure and the onset of mesothelioma.

It may take 10 – 50 years after asbestos exposure for a patient to develop symptoms. The median mesothelioma latency period is about 30 years. Studies indicate no significant statistical difference in latency period between pleural and peritoneal mesothelioma patients.

However, latency period may be affected by many other factors, including patient characteristics and occupation.

• Age: Some research indicates that the younger someone is at first exposure, the longer their latency period may be. For example, in one study individuals exposed before age 20 had a median latency of about 40 years. Patients exposed at 50 or older had a median latency of about 10 years.
• Occupation: People in certain occupations may face long-term or intense periods of asbestos exposure. As a result, they may be more likely to develop mesothelioma and have a shorter latency period. An Italian study measured the latency periods of people who had asbestos-related jobs. Insulators showed the shortest latency period at about 30 years. Women who experienced household exposure showed the longest period at about 50 years.

Occupations With High Asbestos Exposure Risk

Occupational asbestos exposure can affect people in many types of jobs. As discussed above, certain occupations may be associated with different latency periods. Similarly, certain occupations may be associated with increased risk of asbestos exposure and related disease development.

Some of the occupations with the highest risk of asbestos exposure include:

• Aircraft mechanics
• Auto mechanics
• Boiler workers
• Construction workers
• Firefighters
• HVAC workers
• Industrial workers
• Insulators
• Machine operators
• Machinists
• Mine workers
• Oil refinery workers
• Shipyard workers
• Textile mill workers

Mesothelioma Statistics by Age and Gender or Sex

Mesothelioma is more commonly diagnosed among male than female patients. Some research links this difference to men being at higher risk of occupational exposure during the height of asbestos use.

The latency period also affects age-related statistics. Mesothelioma symptoms typically take 10 – 50 years to develop, which increases the age at diagnosis. The average age at mesothelioma diagnosis may also differ with the type of mesothelioma.

• Peritoneal mesothelioma: Average age at diagnosis for peritoneal mesothelioma patients is about 51 years.
• Pleural mesothelioma: Average age at diagnosis for pleural mesothelioma patients is about 67 years.

The following statistics were gathered from the most recent data available from the CDC and the National Cancer Institute (NCI).

Mesothelioma Incidence Statistics From 1999 to 2019

• Diagnoses by sex: 51,354 male individuals and 15,597 female individuals were diagnosed with mesothelioma in the United States.
• Diagnoses among those 80 years old and older: 19,179 cases
• Diagnoses among those 75 – 79 years old: 12,521 cases
• Diagnoses among those 70 – 74 years old: 11,021 cases
• Diagnoses among those 65 – 69 years old: 8,678 cases
• Diagnoses among those 60 – 64 years old: 6,091 cases
• Diagnoses among those 59 years old and younger: 9,447 cases

Mesothelioma Incidence by Race

The connection between race and mesothelioma incidence has not been fully studied. White, non-Hispanic people seem to have a higher incidence, but this may not be a true difference.

Race	Number of Cases Diagnosed in 2019
White, Non-Hispanic	2,402
Hispanic	265
Black, Non-Hispanic	152
Asian and Pacific Islander, Non-Hispanic	61
American Indian and Alaska Native, Non-Hispanic	31*

_{*This is an estimate based on CDC data for total mesothelioma deaths in the country and deaths among other demographics}

05. Mesothelioma in the U.S.

Mesothelioma Incidence in the United States

Approximately 3,000 new cases of mesothelioma are diagnosed each year in the United States. Additionally, about 2,500 mesothelioma-related deaths occur in the United States each year.

The CDC collects information on both mesothelioma incidence rate and mortality rate (death rate). This data provides information regarding how many patients are diagnosed with mesothelioma and die from the cancer. The most recent information spans from 1999 to 2019 for incidence and 1999 to 2020 for mortality.

• 66,951 Americans were diagnosed with mesothelioma between 1999 and 2019.
• 54,905 Americans died from mesothelioma between 1999 and 2020.
• Mesothelioma mortality rates remain steady. Since 1999, the rate of deaths per one million people has remained between 6 and 9.
• Researchers estimate more than 20 million people in the United States are at risk of developing mesothelioma at some point in their lives.

It is also possible to break down statistics for mesothelioma cases by state. Analyzing statistics in this way may provide insights about geographical areas with more instances of naturally occurring asbestos, prevalence of high-risk occupations and other mesothelioma risk factors.

According to the most recent data available, spanning from 1999 to 2019, the southern United States experienced the most diagnosed cases of mesothelioma. This may be because of factors like more industry in this region or more natural asbestos deposits.

• Southern United States: 21,676 mesothelioma diagnoses
• Midwestern United States: 15,807 mesothelioma diagnoses
• Northeastern United States: 15,325 mesothelioma diagnoses
• Western United States: 14,143 mesothelioma diagnoses

However, broken down by state, Maine, West Virginia, Pennsylvania, Delaware and New Jersey had the highest rates of diagnoses. For states with the highest rates of death, the list is the same except Montana replaces New Jersey.

_{*Diagnoses data from 1999 to 2019
**Mortality data from 1999 to 2020}

Malignant Mesothelioma Cases by Year and Type

List of Malignant Mesothelioma Cases

Year of Diagnosis	Total Cases	Number of Pleural Cases	Number of Peritoneal Cases
1999	2,973	2,715	258
2000	3,056	2,805	251
2001	3,051	2,773	278
2002	3,098	2,783	315
2003	3,138	2,804	334
2004	3,200	2,903	297
2005	3,290	2,942	348
2006	3,209	2,875	334
2007	3,184	2,878	306
2008	3,266	2,925	341
2009	3,295	2,958	337
2010	3,323	2,990	333
2011	3,373	2,972	401
2012	3,294	2,940	354
2013	3,312	2,949	363
2014	3,334	2,903	431
2015	3,303	2,904	399
2016	3,197	2,800	397
2017	3,196	2,804	392
2018	2,948	2,554	394

06. Global Statistics

Mesothelioma Cases Worldwide

Mesothelioma is a global problem stemming from frequent asbestos use around the world in the 20th century. A recent study found an estimated 30,000 deaths occur globally from mesothelioma each year. Although the exact global mortality rate is not confirmed, these statistics demonstrate that mesothelioma cancer is a global issue.

The areas with the highest rates of mesothelioma include the United Kingdom, Australia and Andorra.

Countries With Asbestos Bans

Asbestos exposure is the only known cause of malignant mesothelioma. Exposure to the mineral may also cause asbestosis, lung cancer and other asbestos-related diseases. To prevent these diseases, some countries around the world have banned the carcinogen.

Even with a ban, countries like the United Kingdom continue to face mesothelioma and other asbestos-related diseases because of their long latency periods. A global ban may help reduce mesothelioma incidence over time.

Asbestos is not banned in the United States. However, the Environmental Protection Agency (EPA) proposed a ban of chrysotile asbestos in 2022, which could be a path forward towards a total ban.

07. Common Questions