Abramson Cancer Center at Penn Medicine
Doctors Affiliated with this Treatment Facility
Contact Information
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104
History of Abramson Cancer Center at Penn Medicine
Penn Medicine is the University of Pennsylvania’s academic health system, which integrates the Perelman School of Medicine at the University of Pennsylvania with Penn Medicine’s hospitals and clinical practices. The program’s history includes the following milestones:
- 1973: Cancer specialists founded Penn Medicine’s Cancer Center to advance research and deliver cutting-edge patient care. The center earned National Cancer Institute (NCI) designation that same year.
- 1974: The center became one of the first to receive NCI Comprehensive Cancer Center designation, a status it has maintained ever since.
- 2002: Penn Medicine’s Cancer Center was renamed the Abramson Cancer Center of the University of Pennsylvania in recognition of the philanthropic support of Leonard and Madlyn Abramson and their family.
Today, the Abramson Cancer Center at Penn Medicine delivers cancer care across Penn Medicine’s system. This includes the Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center (PPMC). It also has many outpatient services based in the Perelman Center for Advanced Medicine, which opened in 2014.
The Abramson Cancer Center now supports more than 300 faculty members and 400 scientists. The center also provides access to nearly 600 clinical trials and serves more than 300,000 outpatient visits each year, advancing cancer care for patients locally and worldwide.
Abramson Cancer Center at Penn Medicine Locations
The Abramson Cancer Center at Penn Medicine provides comprehensive cancer care across multiple locations in Philadelphia. Each facility offers expert cancer treatments in addition to other departments and specialties.
Hospital of the University of Pennsylvania
- Location: 3400 Spruce Street, Philadelphia, PA 19104
- Primary specialties: Heart valve disease, inpatient cancer care, lung cancer, obstetrics and maternity care, sleep medicine, stroke care and women’s health
Penn Presbyterian Medical Center
- Location: 51 N 39th Street , Philadelphia, PA 19104
- Primary specialties: Cardiovascular medicine, emergency and trauma services, Penn Mesothelioma and Pleural Program, primary care and surgical services
Perelman Center for Advanced Medicine
- Location: 3400 Civic Center Boulevard, Philadelphia, PA 19104
- Primary specialties: Hematology, outpatient cancer care, pain medicine, palliative and supportive care, physical medicine and rehabilitation and primary care
Mesothelioma Care at Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine treats mesothelioma patients through its Penn Mesothelioma and Pleural Program. The program is located inside the Pavilion for Advanced Care at PPMC and specializes in malignant pleural mesothelioma and related lung diseases.
Expert care teams at Penn Mesothelioma and Pleural Program include pulmonologists, medical oncologists, thoracic surgeons, radiation oncologists and other specialists. They meet regularly to discuss each patient’s case, review test results and talk about treatment options.
Mesothelioma treatment may include surgery, chemotherapy, immunotherapy or radiation. This includes advanced radiation options like proton therapy, which only a few cancer centers in the country provide. The center also provides symptom management and treats lung problems that can co-occur with mesothelioma, such as pleural effusion and talc pleurodesis.
In addition, Abramson Cancer Center at Penn Medicine is a leading center for ongoing research studies and clinical trials for most mesothelioma stages. Their results have led to innovative approaches to mesothelioma treatment, such as CAR T-cell therapy and photodynamic therapy. Doctors at this center can review available clinical trials and determine whether a patient is eligible.
Abramson Cancer Center at Penn Medicine Specializations
- CAR T-cell therapy
- Chemotherapy
- Chronic lung disease
- Immunotherapy
- Interstitial lung disease
- Lung cancer
- Mesothelioma
- Minimally invasive and robotic-assisted surgery
- Photodynamic therapy
- Pleural disease
- Pleural effusion
- Proton therapy
- Pulmonary and respiratory care and rehabilitation
- Radiation therapy
- Surgical oncology
- Talc pleurodesis
- Thoracic oncology and surgery
Abramson Cancer Center at Penn Medicine Accreditations
- American Nurses Credentialing Center Magnet Recognition Program Credential
- Commission on Cancer Accreditation
- NCI-Designated Comprehensive Cancer Center
Mesothelioma Clinical Trials at Abramson Cancer Center at Penn Medicine
The following clinical trials are actively recruiting participants at Abramson Cancer Center and UPenn in Pennsylvania:
Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)
Conditions: Mesothelioma
Last Updated: December 3, 2025
Status: Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Conditions: Mesothelioma
Last Updated: May 12, 2025
Status: Recruiting
SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma
Conditions: Mesothelioma
Last Updated: November 20, 2025
Status: Recruiting
Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors
Conditions: Mesothelioma
Last Updated: September 1, 2025
Status: Recruiting
Patient and Family Services at Abramson Cancer Center at Penn Medicine
The Abramson Cancer Center at Penn Medicine offers a range of resources for patients and families. The integrative oncology program complements standard cancer treatments through managing side effects, recovery and overall well-being. Offerings include:
- Acupuncture
- Art Therapy
- Exercise Classes
- Massage Therapy
- Mindfulness Stress Reduction Program
- Quality of Life Program
- Radiation Oncology Patient Alumni Program
- Reiki Therapy
- Yoga
Additional patient and family services at Abramson Cancer Center include:
- Cancer Center Boutique
- Managing Side Effects
- Nutritional Counseling
- Oncology Nurse and Patient Navigators
- Oncology Social Workers
- Palliative Care at Home
- Patient and Family Counseling
- Pet Therapy
- Stop Smoking Program
- Support Groups and Events
- Survivorship Program
- Transportation to Appointments
Patient and Family Services in the Philadelphia Area
The Abramson Cancer Center at Penn Medicine is located in Philadelphia, Pennsylvania. As a major metropolitan area, Philadelphia offers nearby resources to mesothelioma patients and their families. These offsite services include cancer groups, financial assistance, housing options, survivorship programs and more.
