Probe based confocal laser endomicroscopy (pCLE) is a new optical endoscopic technique, generating fluorescent light emission from the tissue of interest and allowing in vivo live imaging at a cellular level ("optical biopsies"). It was first used in gastroenterology and came later to the light in pulmonary medicine and is still an experimental technique. In gastroenterology, this new investigational technique is used in Barret oesophagus, inflammatory bowel disease, pancreas cystic lesions... Nowadays, there are no data concerning usefullness of endomicroscopy in medical thoracoscopy. During thoracoscopy This new tool could help to target biopsies or help clinicians to do the right diagnosis early, allowing rapid therapeutic intervention (talc pleurodesis for example) . Furthermore, some details can be studied only during live imaging as microorganisms or bloodflows. We performed an endomicroscopy to every patient needing a thoracoscopy (no matter the indication) and who agreed to participate. We Compared endomicroscopy diagnosis and pathologic diagnosis to assess the ability of this new tool to diagnose a pleural carcinomatosis.
|First Received Date||January 13, 2019|
|Last Changed Date||January 15, 2019|
|Start Date||May 22, 2018|
|Anticipated Primary Completion Date||December 20, 2019|
|Primary Outcome Measures||
Pleural carcinomatosis identification (compared to standard biopsies) [Time Frame: One day.]
|Study Arms / Comparison Groups||0 / 1|
|Ages||18 Years - N/A|
|Accepts Healthy Volunteers||No|
Olivier Bonhomme, MD
- Every patient refered for a medical thoracoscopy and willing to participate.
- < 18 ans
|Responsible Party||Principal Investigator|
|Sponsor||University Hospital of Liege|
|Verification Date||January 2019|