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Several mesothelioma clinical trials are in progress but are not recruiting new patients. In these studies, the enrollment period has ended and new patients can not be added. Patients currently enrolled in these studies help doctors test the effectiveness of emerging mesothelioma treatments.


01. Ongoing Clinical Trials

Ongoing Mesothelioma Clinical Trials

Clinical trials are currently in progress to evaluate new mesothelioma treatment protocols. Ongoing clinical trials may accept new patients while testing on already enrolled patients. However, this timeframe is often short and then no new patients are admitted to the trials. Please note that the enrollment period for the following mesothelioma studies has concluded and no new participants are being recruited at this time.

The purpose of these studies is to determine both the safety and effectiveness of new mesothelioma drugs and treatment therapies. Click on a link to learn more about a study and to get updated information.

02. List of Ongoing Clinical Trials

List of Ongoing Mesothelioma Clinical Trials Not Recruiting Patients

Provided below is a list of mesothelioma clinical trials that are not recruiting or enrolling participants. Click on a link to learn more about each study.

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors


Conditions: Carcinoma, Renal Cell, Mesothelioma

Last Updated: August 26, 2021

Status: Active, not recruiting

Locations: Mobile, AL. Scottsdale, AZ. Tucson, AZ. Baltimore, MD. Boston, MA. Boston, MA. Detroit, MI. Nashville, TN. Nashville, TN. Houston, TX. Houston, TX. San Antonio, TX.

First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin


Conditions: Mesothelioma

Last Updated: August 17, 2021

Status: Active, not recruiting

Locations: Bethesda, MD. Houston, TX.

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma


Conditions: Mesothelioma, Lung Neoplasms

Last Updated: August 12, 2021

Status: Active, not recruiting

Locations: Rogers, AR. Antioch, CA. Burbank, CA. Fremont, CA. Fresno, CA. Los Angeles, CA. Los Angeles, CA. Modesto, CA. Oakland, CA. Orange, CA. Redwood City, CA. Richmond, CA. Roseville, CA. Sacramento, CA. Sacramento, CA. Sacramento, CA. San Francisco, CA. San Jose, CA. San Leandro, CA. San Rafael, CA. Santa Clara, CA. Santa Rosa, CA. South San Francisco, CA. Stockton, CA. Vacaville, CA. Vallejo, CA. Walnut Creek, CA. Hartford, CT. Orlando, FL. Gainesville, GA. 'Aiea, HI. 'Aiea, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Honolulu, HI. Kailua, HI. Lihue, HI. Boise, ID. Coeur d'Alene, ID. Post Falls, ID. Sandpoint, ID. Bloomington, IL. Bloomington, IL. Canton, IL. Carbondale, IL. Carthage, IL. Centralia, IL. Decatur, IL. Decatur, IL. Decatur, IL. Effingham, IL. Eureka, IL. Galesburg, IL. Galesburg, IL. Kewanee, IL. Macomb, IL. O'Fallon, IL. Ottawa, IL. Ottawa, IL. Pekin, IL. Pekin, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peru, IL. Peru, IL. Princeton, IL. Springfield, IL. Springfield, IL. Springfield, IL. Springfield, IL. Beech Grove, IN. Indianapolis, IN. Richmond, IN. Topeka, KS. Crestview Hills, KY. Lexington, KY. Ann Arbor, MI. Ann Arbor, MI. Ann Arbor, MI. Dearborn, MI. Detroit, MI. Detroit, MI. Detroit, MI. Farmington Hills, MI. Flint, MI. Flint, MI. Flint, MI. Jackson, MI. Lansing, MI. Livonia, MI. Pontiac, MI. Port Huron, MI. Saginaw, MI. Warren, MI. Pascagoula, MS. Bonne Terre, MO. Cape Girardeau, MO. Cape Girardeau, MO. Jefferson City, MO. Saint Louis, MO. Sainte Genevieve, MO. Sullivan, MO. Sunset Hills, MO. Anaconda, MT. Billings, MT. Billings, MT. Billings, MT. Billings, MT. Bozeman, MT. Butte, MT. Great Falls, MT. Great Falls, MT. Helena, MT. Kalispell, MT. Kalispell, MT. Missoula, MT. Missoula, MT. Missoula, MT. Charlotte, NC. Charlotte, NC. Charlotte, NC. Charlotte, NC. Hendersonville, NC. Hendersonville, NC. Huntersville, NC. Huntersville, NC. Matthews, NC. Matthews, NC. Mooresville, NC. Statesville, NC. Winston-Salem, NC. Belpre, OH. Chillicothe, OH. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Columbus, OH. Columbus, OH. Columbus, OH. Columbus, OH. Columbus, OH. Columbus, OH. Columbus, OH. Columbus, OH. Dayton, OH. Dayton, OH. Dayton, OH. Dayton, OH. Dayton, OH. Delaware, OH. Delaware, OH. Delaware, OH. Fairfield, OH. Findlay, OH. Franklin, OH. Greenville, OH. Kettering, OH. Lancaster, OH. Mansfield, OH. Marietta, OH. Marion, OH. Mount Vernon, OH. Newark, OH. Newark, OH. Portsmouth, OH. Springfield, OH. Troy, OH. Westerville, OH. Xenia, OH. Zanesville, OH. Clackamas, OR. Milwaukie, OR. Newberg, OR. Oregon City, OR. Portland, OR. Portland, OR. Boiling Springs, SC. Easley, SC. Greenville, SC. Greenville, SC. Greenville, SC. Greenville, SC. Greenville, SC. Greer, SC. Seneca, SC. Bristol, TN. Bristol, TN. Johnson City, TN. Kingsport, TN. Kingsport, TN. Houston, TX. Danville, VA. Norton, VA. Anacortes, WA. Bellingham, WA. Bremerton, WA. Burien, WA. Edmonds, WA. Issaquah, WA. Kennewick, WA. Kirkland, WA. Longview, WA. Mount Vernon, WA. Poulsbo, WA. Seattle, WA. Seattle, WA. Seattle, WA. Seattle, WA. Seattle, WA. Seattle, WA. Seattle, WA. Sedro-Woolley, WA. Spokane, WA. Spokane, WA. Spokane, WA. Vancouver, WA. Vancouver, WA. Wenatchee, WA. Casper, WY. Cody, WY. Cody, WY. Sheridan, WY.

A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies


Conditions:

Last Updated: August 11, 2021

Status: Active, not recruiting

Locations: Chicago, IL. Bethesda, MD. Nashville, TN. Dallas, TX.

A Study of Rebastinib (DCC-2036) in Combination With Carboplatin in Patients With Advanced or Metastatic Solid Tumors


Conditions: Neoplasms

Last Updated: August 10, 2021

Status: Active, not recruiting

Locations: San Francisco, CA. Santa Monica, CA. Chicago, IL. Kansas City, KS. Charlotte, NC. Columbus, OH. Nashville, TN. Houston, TX. San Antonio, TX.

A Study of LY3023414 in Participants With Advanced Cancer


Conditions: Neoplasms, Mesothelioma

Last Updated: August 5, 2021

Status: Active, not recruiting

Locations: Los Angeles, CA. New York, NY. Oklahoma City, OK. Philadelphia, PA. Nashville, TN. Nashville, TN.

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma


Conditions: Mesothelioma, Lung Neoplasms

Last Updated: July 30, 2021

Status: Active, not recruiting

Locations: Phoenix, AZ. Scottsdale, AZ. Hot Springs, AR. Arroyo Grande, CA. Duarte, CA. Sacramento, CA. Colorado Springs, CO. Colorado Springs, CO. Denver, CO. Durango, CO. Durango, CO. Golden, CO. Lakewood, CO. Lakewood, CO. Littleton, CO. Longmont, CO. Longmont, CO. Parker, CO. Parker, CO. Pueblo, CO. Pueblo, CO. Thornton, CO. Jacksonville, FL. Boise, ID. Caldwell, ID. Coeur d'Alene, ID. Meridian, ID. Nampa, ID. Post Falls, ID. Sandpoint, ID. Aurora, IL. Bloomington, IL. Canton, IL. Carbondale, IL. Carterville, IL. Carthage, IL. Centralia, IL. Danville, IL. Decatur, IL. Decatur, IL. Effingham, IL. Effingham, IL. Eureka, IL. Galesburg, IL. Galesburg, IL. Kewanee, IL. Macomb, IL. Mattoon, IL. O'Fallon, IL. Ottawa, IL. Pekin, IL. Pekin, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peru, IL. Peru, IL. Princeton, IL. Springfield, IL. Springfield, IL. Springfield, IL. Swansea, IL. Urbana, IL. Urbana, IL. Yorkville, IL. Ames, IA. Ames, IA. Boone, IA. Clive, IA. Clive, IA. Council Bluffs, IA. Creston, IA. Des Moines, IA. Des Moines, IA. Fort Dodge, IA. Jefferson, IA. Marshalltown, IA. West Des Moines, IA. Lawrence, KS. Wichita, KS. Wichita, KS. Wichita, KS. Bardstown, KY. Corbin, KY. Lexington, KY. Lexington, KY. London, KY. Louisville, KY. Louisville, KY. Louisville, KY. Shepherdsville, KY. New Orleans, LA. Brownstown, MI. Clinton Township, MI. Detroit, MI. Jackson, MI. Shelby, MI. West Bloomfield, MI. Rochester, MN. Bonne Terre, MO. Cape Girardeau, MO. Cape Girardeau, MO. Jefferson City, MO. Saint Louis, MO. Sainte Genevieve, MO. Sullivan, MO. Sunset Hills, MO. Anaconda, MT. Billings, MT. Bozeman, MT. Great Falls, MT. Great Falls, MT. Helena, MT. Kalispell, MT. Missoula, MT. Grand Island, NE. Kearney, NE. Kearney, NE. Lincoln, NE. Omaha, NE. Omaha, NE. Omaha, NE. Omaha, NE. Omaha, NE. Papillion, NE. Henderson, NV. Henderson, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Reno, NV. Reno, NV. Reno, NV. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Lawton, OK. Oklahoma City, OK. Pittsburgh, PA. Charleston, SC. Chattanooga, TN. Hixson, TN. Ooltewah, TN. Bryan, TX. Conroe, TX. Dallas, TX. Houston, TX. Houston, TX. Houston, TX. League City, TX. Richardson, TX. Sugar Land, TX. Charlottesville, VA. Bellevue, WA. Bremerton, WA. Bremerton, WA. Burien, WA. Enumclaw, WA. Federal Way, WA. Lakewood, WA. Poulsbo, WA. Renton, WA. Seattle, WA. Seattle, WA. Seattle, WA. Tacoma, WA. Tacoma, WA. Cody, WY. Sheridan, WY.

A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors


Conditions: Neoplasms

Last Updated: July 29, 2021

Status: Active, not recruiting

Locations: La Jolla, CA. Sacramento, CA. Stanford, CA. New Haven, CT. Huntersville, NC. Greenville, SC. Dallas, TX. San Antonio, TX. Charlottesville, VA. Fairfax, VA.

Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma


Conditions: Mesothelioma

Last Updated: July 28, 2021

Status: Active, not recruiting

Locations: Alessandria, Alabama. Catania, Connecticut.

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin


Conditions: Neoplasms, Mesothelioma, Lung Neoplasms

Last Updated: July 23, 2021

Status: Active, not recruiting

Locations: Duarte, CA. Los Angeles, CA. Los Angeles, CA. Pasadena, CA. Sacramento, CA. Aurora, CO. Baltimore, MD. Ann Arbor, MI. Rochester, MN. Columbus, OH. Pittsburgh, PA. Nashville, TN. Nashville, TN. Madison, WI.

Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma


Conditions: Mesothelioma, Lung Neoplasms

Last Updated: July 22, 2021

Status: Active, not recruiting

Locations: Scottsdale, AZ. La Jolla, CA. Los Angeles, CA. San Francisco, CA. Santa Monica, CA. New Haven, CT. Newark, DE. Tampa, FL. Augusta, GA. Chicago, IL. Peoria, IL. Baltimore, MD. Baltimore, MD. Minneapolis, MN. New York, NY. Rochester, NY. Durham, NC. Canton, OH. Philadelphia, PA. Dallas, TX. Houston, TX.

Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma


Conditions: Mesothelioma

Last Updated: June 15, 2021

Status: Active, not recruiting

Locations: Houston, TX.

Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesothelioma


Conditions: Mesothelioma, Lung Neoplasms

Last Updated: June 11, 2021

Status: Active, not recruiting

Locations: Basking Ridge, NJ. Middletown, NJ. Commack, NY. Harrison, NY. New York, NY. Rockville Centre, NY. Uniondale, NY.

Tazemetostat Rollover Study (TRuST): An Open-Label, Rollover Study


Conditions: Lymphoma, Sarcoma, Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse, Mesothelioma, Sarcoma, Synovial, Carcinoma, Medullary

Last Updated: May 26, 2021

Status: Active, not recruiting

Locations: Tucson, AZ. Tampa, FL. Ann Arbor, MI. New York, NY. New York, NY.

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies


Conditions: Neoplasms

Last Updated: May 21, 2021

Status: Active, not recruiting

Locations: Los Angeles, CA. Gainesville, FL. Detroit, MI. Saint Louis, MO. Hackensack, NJ. New York, NY. Chapel Hill, NC. Oklahoma City, OK. Portland, OR. Philadelphia, PA. Pittsburgh, PA. Nashville, TN. Dallas, TX. Houston, TX. Seattle, WA.

Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesothelioma


Conditions: Mesothelioma

Last Updated: May 20, 2021

Status: Active, not recruiting

Locations: La Jolla, CA. Los Angeles, CA. Stanford, CA. Aurora, CO. Miami, FL. Atlanta, GA. Chicago, IL. Evanston, IL. Baltimore, MD. Ann Arbor, MI. Saint Louis Park, MN. Saint Louis, MO. New Brunswick, NJ. New York, NY. Philadelphia, PA. Pittsburgh, PA. Dallas, TX. Fairfax, VA. Seattle, WA. Wauwatosa, WI.

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma


Conditions: Mesothelioma

Last Updated: May 19, 2021

Status: Active, not recruiting

Locations: Los Angeles, CA. San Francisco, CA. Tampa, FL. Kansas City, KS. Baltimore, MD. Baltimore, MD. Minneapolis, MN. Rochester, MN. New York, NY. Philadelphia, PA. Dallas, TX.

Psychosocial Needs and Exploration of Online Support for Patients With Mesothelioma


Conditions: Mesothelioma

Last Updated: May 10, 2021

Status: Active, not recruiting

Locations: New York, NY.

A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors


Conditions: Neoplasms

Last Updated: May 3, 2021

Status: Active, not recruiting

Locations: La Jolla, CA. Chicago, IL. Huntersville, NC. San Antonio, TX. Fairfax, VA.

Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies


Conditions: Neoplasms, Peritoneal Neoplasms

Last Updated: April 29, 2021

Status: Active, not recruiting

Locations: Boston, MA.

Intraperitoneal MCY-M11 (Mesothelin-targeting CAR) for Treatment of Advanced Ovarian Cancer and Peritoneal Mesothelioma


Conditions: Adenocarcinoma, Mesothelioma, Carcinoma, Ovarian Epithelial

Last Updated: April 23, 2021

Status: Active, not recruiting

Locations: Rockville, MD. Boston, MA. Saint Louis, MO. Hackensack, NJ.

TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patients


Conditions: Mesothelioma

Last Updated: April 11, 2021

Status: Active, not recruiting

Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients


Conditions: Mesothelioma

Last Updated: March 24, 2021

Status: Active, not recruiting

Locations: San Francisco, CA. New Haven, CT. Tampa, FL. Chicago, IL. Baltimore, MD. Detroit, MI. Grand Rapids, MI. Rochester, MN. New York, NY. Cleveland, OH. Jefferson Hills, PA. Philadelphia, PA. Houston, TX. Morgantown, WV.

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies


Conditions: Carcinoma, Merkel Cell, Carcinoma, Lung Neoplasms, Melanoma, Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms, Mesothelioma, Squamous Cell Carcinoma of Head and Neck

Last Updated: March 16, 2021

Status: Active, not recruiting

Locations: Los Angeles, CA. Jackson, MS. Hackensack, NJ. Huntsville, NC.

Screening of Alberta Asbestos Exposed Workers for Lung Cancer and Mesothelioma


Conditions: Lung Neoplasms, Mesothelioma

Last Updated: March 4, 2021

Status: Active, not recruiting

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors


Conditions: Carcinoma, Merkel Cell, Carcinoma, Carcinoma, Squamous Cell, Mesothelioma, Neuroendocrine Tumors, Nasopharyngeal Carcinoma, Lung Neoplasms, Carcinoma, Neuroendocrine

Last Updated: February 23, 2021

Status: Active, not recruiting

Locations: Houston, TX.

PembROlizuMab Immunotherapy Versus Standard Chemotherapy for Advanced prE-treated Malignant Pleural Mesothelioma


Conditions: Mesothelioma

Last Updated: February 8, 2021

Status: Active, not recruiting

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma


Conditions: Vaccinia, Mesothelioma, Pleural Effusion, Malignant, Pleural Effusion

Last Updated: January 19, 2021

Status: Active, not recruiting

Locations: New York, NY.

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549


Conditions: Carcinoma, Non-Small-Cell Lung, Melanoma, Triple Negative Breast Neoplasms, Mesothelioma, Neoplasms, Squamous Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Adrenocortical Carcinoma

Last Updated: December 3, 2020

Status: Active, not recruiting

Locations: San Diego, CA. Santa Monica, CA. Port Saint Lucie, FL. Atlanta, GA. Boston, MA. Boston, MA. Boston, MA. Hackensack, NJ. New York, NY. Houston, TX. San Antonio, TX.

MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesothelioma


Conditions: Mesothelioma

Last Updated: October 19, 2020

Status: Active, not recruiting

Locations: Houston, TX.

Genetically Modified T Cells in Treating Patients With Stage III-IV Non-small Cell Lung Cancer or Mesothelioma


Conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung, Mesothelioma

Last Updated: June 30, 2020

Status: Active, not recruiting

Locations: Seattle, WA.

Intracavitary Cisplatin-Fibrin Localized Chemotherapy After P/D or EPP for Malignant Pleural Mesothelioma


Conditions: Mesothelioma

Last Updated: May 26, 2020

Status: Active, not recruiting

Pembrolizumab in Treating Patients With Malignant Mesothelioma


Conditions: Mesothelioma, Lung Neoplasms

Last Updated: April 27, 2020

Status: Active, not recruiting

Locations: Chicago, IL.

CheckpOiNt Blockade For Inhibition of Relapsed Mesothelioma


Conditions: Mesothelioma

Last Updated: April 20, 2020

Status: Active, not recruiting

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