Dr. Jack A. Elias is the Senior Vice President of Health Affairs and Dean of Medicine and Biological Sciences at Brown University in Providence, Rhode Island. Prior to coming to Brown University, he held positions at the University of Pennsylvania and was Chief of Pulmonary and Critical Care Medicine and Chair of the Department of Medicine at the Yale School of Medicine. Dr. Elias’s clinical interests include asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease and acute lung injury. He also has a number of research interests including cellular and molecular pathogenesis of asthma and COPD as well as cellular and molecular mechanisms of lung injury repair and remodeling. He has studied transgenic modeling of pulmonary diseases and disorders, effector mechanisms of IL-13, VEGF, and TGF-beta type cytokines in the lung, and effector mechanisms for the TH2 and Th1 cytokines in the lung. Like mesothelioma, pleural pulmonary disease has been linked to asbestos.
Dr. Elias has received a number of awards over the course of his medical career, including the Recognition Award for Scientific Accomplishment from the American Thoracic Society, as well as four RO1 awards and a T32 training grant in Pulmonary Biology. As a respected expert on lung inflammation, injury and repair, Dr. Elias was the first to translate pathogenic mechanisms in models to humans and human disorders.
Main Specialty: Pulmonary, Critical Care
Other Interests & Specialties: Pulmonology, general pulmonary medicine, asthma, immune and allergic disorders, chronic obstructive pulmonary disease, effects of smoking, intensive care and interstitial lung diseases.
Certifications, Awards & Accolades: American Board of Internal Medicine and American Board of Allergy and Immunology Certifications, American Board of Internal Medicine Certification, Edward Livingston Trudeau Scholar, Leonard Dalsemer Scholar, Career Investigator Award from the American Lung Association, Recognition Award for Scientific Achievement from the American Thoracic Society, member of the ASCI, Council of National Heart Lung and Blood Institute, Alpha Omega Alpha and IOM elected member
Education & Experience:
- Undergraduate Degree from University of Pennsylvania
- Medical Degree from University of Pennsylvania
- Residency at Tufts-New England Medical Center
- Residency in Medicine at the University of Pennsylvania
- Fellowship in Pulmonary and Critical Care Medicine at University of Pennsylvania Medical Center
- Fellowship in Allergy and Clinical Immunology at the University of Pennsylvania
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. The International Journal of Biochemistry & Cell Biology. January 2011;43(1):154-162. doi: 10.1016/j.biocel.2010.10.013
Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-γ. Experimental & Molecular Medicine. February 2011;343:169-178. doi: 10.3858/emm.2011.43.4.018
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