Median life expectancy for mesothelioma patients usually ranges from 12 to 21 months, depending on the stage of the disease at diagnosis, with approximately 40 percent of patients living beyond one year and 20 percent living beyond 2 years.
Malignant mesothelioma is an aggressive form of cancer whose symptoms typically don’t show up until later stages. Therefore, life expectancy for mesothelioma patients is generally short.
Life expectancy varies significantly from patient to patient based on a number of individual factors and circumstances. Long-term survival is extremely rare, with fewer than 10 percent of patients living beyond 5 years.
Factors Affecting Life Expectancy
The life expectancy of a mesothelioma patient is a complex thing to determine, as it depends on a variety of factors.
An early diagnosis can improve life expectancy significantly. When diagnosed at an early stage (Stage I or Stage II), there is little or no spreading, and treatments are likely to be more effective. However, at Stages III and IV the mesothelioma has expanded beyond the initial location, which makes treatment more difficult.
Another big factor that can affect life expectancy is where the mesothelioma develops. Historically, patients with pleural mesothelioma have had a slightly longer life expectancy than those with peritoneal mesothelioma, while patients diagnosed with peritoneal mesothelioma have a very short life expectancy. However, in recent years, the life expectancy of patients diagnosed with peritoneal mesothelioma has improved, due to the development of more effective treatments.
Generally, older mesothelioma patients have shorter life expectancies, mostly because they are in poorer health and the disease is likely to be at a later stage. One study showed that individuals diagnosed with pleural mesothelioma before the age of 65 lived almost 4 months longer than those diagnosed at age 65, and more than 8 months longer than those diagnosed at age 75 or older.
Pleural Mesothelioma Life Expectancy
by Age at Diagnosis
|Up to 65 years||12 months|
|65+ years||8 months|
|75+ years||< 4 months|
Mesothelioma can be categorized into three different cell types: epithelioid, sarcomatoid, and biphasic (a mixture of both epithelioid and sarcomatoid cells). Typically, those with epithelioid mesothelioma have a significantly longer life expectancy than those with sarcomatoid mesothelioma, while those with biphasic mesothelioma have a life expectancy in-between.
|Epithelioid||19 months||54 months|
|Biphasic||13 months||4.6 months|
|Sarcomatoid||8 months||Not enough data|
Fewer women have mesothelioma than men, mostly due to occupational differences and risk of asbestos exposure, and life expectancy in women diagnosed with mesothelioma tends to be longer than for men. In general, women diagnosed with mesothelioma live about 5.5 months longer than men with mesothelioma.
Resources for Mesothelioma Patients and their Families
- Request a Free Mesothelioma Treatment Guide
- Connect with Top Mesothelioma Doctors
- Locate the Nearest Comprehensive Cancer Center
Other Factors Affecting Mesothelioma Life Expectancy
Many other factors can go into determining a patient’s life expectancy, from overall health of the individual to gender to certain genetic factors. The table below provides a list of things that can affect life expectancy positively and negatively.
|Positive Factors||Negative Factors|
|No history of smoking||History of smoking|
|Normal white blood cell count||Elevated white blood cell count|
|Low hemoglobin level||High hemoglobin level|
|Low platelet count||High platelet count|
|No symptoms||Symptoms present|
How these factors affect life expectancy can vary significantly from individual to individual.
Life Expectancy and Mesothelioma Treatment
Patients diagnosed with early-stage mesothelioma may be eligible for an aggressive treatment program, such as involving surgical removal of the tumor combined with chemotherapy or radiation. The surgery is an extensive procedure, so the patient must be in generally good health and not advanced in age.
Patients who can withstand such aggressive treatments often have a better life expectancy and a change at long-term survival beyond five years. When developing a treatment program, the oncologist will assess the patient’s health and ability to undergo such treatments.
Costs and Life Expectancy
No matter what your life expectancy, mesothelioma is a costly disease. From diagnosis to treatment, the medical bills can pile up significantly – and for those who have longer life expectancies, the costs of follow-up visits, continued medications, and other ongoing expenses will build over time. Furthermore, many people with mesothelioma are unable to work, making it that much harder to pay for tests and treatments.
If you or a loved one has been diagnosed with mesothelioma, learn more about what financial assistance is available.Sources
Alexander, H.R., and Burke, A.P. “Diagnosis and management of patients with malignant peritoneal mesothelioma.” Journal of Gastrointestinal Oncology. 2016;7(1):79-86. doi:10.3978/j.issn.2078-6891.2015.134
Rusch, V.W., et al. “Initial Analysis of the International Association For the Study of Lung Cancer Mesothelioma Database.” Journal of Thoracic Oncology. 2012;7(11):1631-1639. doi:10.1097/JTO.0b013e31826915f1
“Survival statistics for mesothelioma.” American Cancer Society. Feb. 17, 2016.