Treating Mesothelioma in South Carolina
South Carolina’s leading cancer centers and specialists offer patients access to advanced mesothelioma care. For example, Hollings Cancer Center at the Medical University of South Carolina (MUSC) in Charleston provides expert teams that can perform a wide range of treatments.
Mesothelioma treatment plans are personalized and may include:
- Surgery: To remove tumors and improve quality of life
- Chemotherapy: To complement other treatments through weakening cancer cells
- Radiation therapy: To shrink tumors and ease symptoms
- Immunotherapy: To help the immune system recognize and attack cancer
- Palliative care: To provide symptom relief, pain management and emotional support
Some patients qualify for clinical trials, which are experimental therapies based on the latest research. Mesothelioma treatment teams can help these patients assess their eligibility for clinical trials. These teams typically include oncologists, thoracic surgeons, pulmonologists, nutritionists and other support specialists who work together to guide patients through treatment and recovery. With multiple treatment options, supportive care services and access to clinical trials, South Carolina patients have pathways to manage mesothelioma and improve their quality of life.
There were 235 new cases of mesothelioma reported in South Carolina between 2018 and 2022, per CDC data accessed in August 2025. A history of shipbuilding in the state may contribute to this figure.
Top Mesothelioma Cancer Centers in South Carolina
Mesothelioma patients in South Carolina have access to some of the nation’s top cancer care. Specialists at these dedicated cancer centers have the experience required to get the best results from mesothelioma treatment.
A top cancer center in South Carolina is the MUSC Hollings Cancer Center. Located in Charleston, this is the state’s only National Cancer Institute–designated cancer center. Hollings is also recognized as a high-performing hospital by U.S. News & World Report® and accredited by the Commission on Cancer, a quality program of the American College of Surgeons.
This cancer center provides a full range of treatment options including surgery, chemotherapy, radiation therapy and immunotherapy. Patients can also access clinical trials for mesothelioma here. Beyond medical treatment, the center offers supportive services such as counseling, nutrition planning, art therapy and wellness programs to care for the whole patient.
The MUSC Hollings Cancer Center and other cancer centers give South Carolina patients access to advanced treatment options and compassionate care close to home. Learn more below.
South Carolina Mesothelioma Cancer Clinics
Top Doctors Who Treat Mesothelioma in South Carolina
Finding the right doctor is one of the most important things for a mesothelioma patient to do. Because this cancer is rare, it is essential to work with a physician who has direct experience treating mesothelioma and is part of a seasoned team.
When choosing a doctor, patients and families should consider asking these key questions to better understand their expertise:
- How many mesothelioma patients do you treat per year?
- What treatments do you most often recommend or perform for mesothelioma?
- What outcomes have your mesothelioma patients experienced with the treatments you recommend?
- Do you have experience enrolling patients in clinical trials for mesothelioma?
Learn more about surgeons and oncologists in South Carolina below.
South Carolina Mesothelioma Doctors
After selecting a doctor, South Carolina mesothelioma patients may still have questions about their care. Our guide, “25 Questions to Ask Your Mesothelioma Doctor at Your First Appointment,” is designed to help patients and families feel more prepared and confident as they begin treatment.
Resources for Mesothelioma Patients
Mesothelioma Clinical Trials in South Carolina
Clinical trials give mesothelioma patients access to new therapies while helping doctors improve future treatment. These studies may test new treatments such as immunotherapy, targeted drugs or novel surgical techniques.
Your South Carolina mesothelioma doctor can help you determine if participation in a clinical trial is a good fit for you.
The following mesothelioma research studies in South Carolina are in progress or actively recruiting participants.
Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma
Conditions: Mesothelioma
Last Updated: October 28, 2025
Status: Active, not recruiting
Locations: Charleston, SC
Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma
Conditions: Mesothelioma
Last Updated: September 6, 2025
Status: Active, not recruiting
Locations: Boiling Springs, SC; Easley, SC; Greenville, SC; Greer, SC; Seneca, SC
Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies
Conditions: Mesothelioma
Last Updated: June 11, 2025
Status: Completed
Locations: Greenville, SC
Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
Conditions: Mesothelioma
Last Updated: September 30, 2024
Status: Active, not recruiting
Locations: Greenville, SC
A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
Conditions: Mesothelioma
Last Updated: April 21, 2022
Status: Completed
Locations: Greenville, SC
Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy
Conditions: Mesothelioma
Last Updated: August 16, 2021
Status: Completed
Locations: Charleston, SC
Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors
Conditions: Mesothelioma
Last Updated: November 6, 2019
Status: Completed
Locations: Charleston, SC
LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE)
Conditions: Mesothelioma
Last Updated: July 16, 2019
Status: Completed
Locations: Greenville, SC
Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma
Conditions: Mesothelioma
Last Updated: December 5, 2016
Status: Completed
Locations: Spartanburg, SC
Collecting Tumor Samples From Patients With Gynecological Tumors
Conditions: Mesothelioma
Last Updated: October 26, 2016
Status: Completed
Locations: Charleston, SC; Greenville, SC; Spartanburg, SC
Capecitabine in Treating Patients With Malignant Mesothelioma
Conditions: Mesothelioma
Last Updated: July 12, 2016
Status: Completed
Locations: Charleston, SC
Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
Conditions: Mesothelioma
Last Updated: July 11, 2016
Status: Completed
Locations: Greenville, SC
S9810: Gemcitabine Plus Cisplatin in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot Be Removed by Surgery
Conditions: Mesothelioma
Last Updated: October 5, 2012
Status: Completed
Locations: Greenville, SC; Spartanburg, SC
Find Cancer Support Services in South Carolina
Mesothelioma patients in South Carolina can access support services to ease the challenges of treatment and recovery. These include cancer rehabilitation, counseling, diet and nutrition guidance, extended stay housing, oxygen supplies and patient transport. Services like these help patients to manage symptoms, maintain a better quality of life and receive practical assistance during care. Families and caregivers may also benefit from counseling and support groups that can give them the tools to care for themselves and their loved ones. The services below offer support to cancer patients in South Carolina.
South Carolina Treatment Support Services
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Cancer Rehabilitation
- AnMed Health Oncology Rehabilitation Anderson 864-512-1505
- Gibbs Cancer Center Oncology Rehabilitation Spartanburg 864-560-1970
- Prisma Health Cancer Institute Greenville 864-455-1346
- The McLeod Center for Cancer Treatment & Research Florence 843-777-2000
- Trident Medical Center Charleston 843-847-4400
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Counseling & Support
- Cancer Society of Greenville County Greenville 864-232-8439
- Center for Integrative Oncology and Survivorship Greenville 864-455-1346
- Hollings Cancer Center Charleston 843-792-9300
- South Carolina Cancer Alliance Columbia 803-708-4732
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Extended Stay Housing
- Charleston Hope Lodge Charleston 843-958-0930
- Hotel Keys of Hope Columbia 800-227-2345
- Joe's House Statewide 877-563-7468
- The Guest House at McLeod Florence 843-777-7292
-
Oxygen Supplies
- Carolina Homecare Greenville 864-271-8258
- Lincare North Charleston 843-769-4431
- Rotech Lexington 803-534-6236
- Special Care Medical West Columbia 803-926-0161
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Patient Transport
- A Golden Ride Charleston 843-566-4039
- Senior Express Transportation Services Columbia 803-926-7933
- Transport Care Services Columbia 803-661-9662
Common Questions
- Can mesothelioma patients in South Carolina receive legal compensation to help pay for treatment?
Yes. Mesothelioma patients in South Carolina may qualify for financial compensation through asbestos lawsuits, bankruptcy trust fund claims, workers’ compensation or VA benefits. These funds can help cover medical bills, travel and other care-related expenses. Because filing deadlines apply, it’s important to consult an experienced South Carolina mesothelioma lawyer as soon as possible.
- How can I schedule an appointment with a mesothelioma doctor in South Carolina?
Most cancer centers in South Carolina offer online appointment request forms or referral phone lines. You can also ask your primary care provider for a referral. If you’re unsure where to begin, take a look at our cancer center and doctor sections above to find an experienced mesothelioma specialist near you. If you need help selecting the right specialist in South Carolina, we can guide you through the process and connect you with an experienced mesothelioma doctor.
- Are there clinical trials for mesothelioma patients in South Carolina?
Yes. Several South Carolina cancer centers participate in clinical trials that test new treatments, including immunotherapy and chemotherapy, among others. A mesothelioma doctor can help you learn whether you may qualify for a study.
- What support services are available to South Carolina mesothelioma patients?
Patients can access services such as cancer rehabilitation, nutrition counseling, counseling and support groups, transportation assistance and extended stay housing. These programs help patients and families manage treatment and maintain quality of life.
- How much does mesothelioma treatment cost in South Carolina?
In South Carolina, mesothelioma treatment can be expensive, even reaching hundreds of thousands of dollars per year. Costs may include those for surgery, chemotherapy, radiation, immunotherapy, imaging scans or hospital stays. Insurance may not cover all of these expenses, and patients often face additional costs for travel and lodging. Financial assistance through settlements, trust funds or veterans’ benefits can help cover these expenditures.
