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01. History

History of City of Hope

City of Hope was founded in 1913 as a free tuberculosis hospital by the Jewish Consumptive Relief Association. Originally called the Los Angeles Sanatorium, the hospital attracted the patronage of Hollywood celebrities and philanthropists. In 1949, the hospital officially changed its name to City of Hope, reflecting a new goal of creating a full-service center for research, treatment and education, with a focus on compassionate patient care.

From its original 40 acres, the campus has expanded over the years to more than 100 acres. A research institute was established in 1952, and Hope Village, which allowed patients and their loved ones to stay together near the hospital during treatment. As City of Hope’s physical presence grew, so did its research efforts, with Hope physicians and scientists pioneering studies in neurogenetics, recombinant DNA and tumor development. In 1983, the Beckman Research Institute was founded with an initial grant of $10 million from the Arnold and Mabel Beckman Foundation. In the late 1990s, City of Hope was awarded the National Cancer Institute’s Comprehensive Cancer Center designation, identifying it as a top cancer center for research and patient care.

02. Mesothelioma Care

Mesothelioma Care at City of Hope

City of Hope offers cancer treatment and care to malignant mesothelioma patients with a specific focus on pleural mesothelioma. Their multidisciplinary team includes experts in treating aggressive and advanced thoracic cancers.

The mesothelioma experts at the City of Hope Cancer Center practice standard treatment techniques, such as surgery, chemotherapy and radiation therapy, but also focus on emerging treatments through clinical trials.

For mesothelioma patients undergoing surgery, their experts prefer minimally invasive options that will cause the least amount of harm on the body with the fastest recovery time. City of Hope stands out from other cancer centers in their use of newer radiation therapies, such as Helical TomoTherapy, four-dimensional computed tomography, intensity-modulated radiation therapy and stereotactic body radiation.

In addition to offering support for patients and their families during their treatment journey, City of Hope offers strong survivorship programs for those that have successfully completed treatment.

03. Specializations

City of Hope Specializations

  • Aggressive and late-stage lung cancers
  • Minimally invasive thoracic surgeries
  • Pleural mesothelioma
04. Accreditations

City of Hope Accreditations

  • National Cancer Institute Designated Comprehensive Cancer Center
  • National Comprehensive Cancer Network
  • U.S. News Best Hospitals for Cancer designation
05. Mesothelioma Clinical Trials

Mesothelioma Clinical Trials at City of Hope

The following clinical trials are in progress or actively recruiting participants at City of Hope:

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma


Conditions: Mesothelioma, Mesothelioma, Malignant

Last Updated: December 2, 2021

Status: Recruiting

Locations: Birmingham, AL. Phoenix, AZ. Scottsdale, AZ. Duarte, CA. La Jolla, CA. Los Angeles, CA. Los Angeles, CA. Newport Beach, CA. Aurora, CO. Aventura, FL. Coral Gables, FL. Deerfield Beach, FL. Jacksonville, FL. Miami, FL. Miami, FL. Plantation, FL. Chicago, IL. Chicago, IL. Lexington, KY. Baltimore, MD. Baltimore, MD. Boston, MA. Boston, MA. Rochester, MN. Creve Coeur, MO. Saint Louis, MO. Saint Louis, MO. Saint Peters, MO. Durham, NC. Pittsburgh, PA. Dallas, TX. Salt Lake City, UT.

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas


Conditions: Adenocarcinoma, Sarcoma, Mesothelioma, Mesothelioma, Malignant, Sarcoma, Ewing, Chondrosarcoma

Last Updated: August 12, 2022

Status: Recruiting

Locations: Scottsdale, AZ. Duarte, CA. Los Angeles, CA. Santa Monica, CA. Aurora, CO. Atlanta, GA. Chicago, IL. Ann Arbor, MI. Grand Rapids, MI. New York, NY. Cleveland, OH. Philadelphia, PA. Houston, TX. San Antonio, TX.

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion


Conditions: Neoplasms

Last Updated: July 22, 2022

Status: Recruiting

Locations: Scottsdale, Arizona. Duarte, California. Indianapolis, Indiana. Baltimore, Maryland. Boston, Massachusetts. New York, New York. New York, New York. Oklahoma City, Oklahoma. Nashville, Tennessee. Houston, Texas. San Antonio, Texas.