Mesothelioma Radiation

Radiation therapy is one of the oldest forms of mesothelioma cancer treatment available, though it has consistently become more sophisticated as the years have passed. The techniques now available to deliver the radiation have resulted in more targeted therapy and better results. For mesothelioma patients, radiation is often used together with chemotherapy for optimal results, or may be used after a form of surgery that is designed to remove as much of the cancer as possible. It may also be employed to relieve some of the symptoms of mesothelioma disease and make the patient more comfortable.

Types of Mesothelioma Radiation

External Beam Radiation

The oldest and most widely used form of radiation therapy is known as external beam radiation.  This is the "original" form of radiation treatment and the type with which most people are familiar.

External beam radiation is administered by means of a machine that delivers an external source of radiation directly to the affected area where the tumor is located. This machine slowly moves around the body but does not touch it. As such, this particular kind of cancer treatment is painless and can be delivered at an outpatient facility, so no hospital stays are necessary.

As with all forms of radiation therapy, the external beam variety is intended to kill cancer cells and to stop them from multiplying. Dosages of radiation involved in this type of treatment are fairly high and can reach areas of the body other than the tumor. Therefore, healthy cells are also sometimes affected.

Generally, external beam mesothelioma radiation is administered five times per week for anywhere from one or two to several weeks. The recommended dosage and length of therapy will depend on a number of factors including the type of cancer, its location, its size, the general overall health of the patient, and which other treatments are being used at the same time. Most sessions last anyone from 10 to 30 minutes, rarely longer.

During treatment, the patient is asked to lie flat on a table and certain parts of the body that should not be exposed to the radiation may be covered with shields that deflect the beams. During the treatment, the technician will be in another room controlling the radiation machine but will be able to talk to the patient through an intercom system. The patient should expect to hear clicking, whirring, and other noises, which are completely normal and are merely indicators that the machine is working properly. If there is any concern, the patient can speak to the technician via the intercom and voice their concerns.

Brachytherapy

Mesothelioma Brachytherapy - also known as internal radiation therapy - is a targeted form of treatment that delivers high doses of radiation directly to the tumor. Greek for “short distance” therapy, this variety of radiation therapy has not been around as long as the external beam type but has shown great promise in the treatment of a number of different kinds of cancer, including mesothelioma.

The process of delivering radiation via brachytherapy involves the implantation of tiny radioactive seeds or rods in or near the tumor. This method allows highly-concentrated doses to reach the area of most concern, and because delivery is so precise, fewer healthy cells are affected during the treatment process.

There are two types of brachytherapy offered - temporary and permanent. The former involves the implantation of seeds for a pre-designated short period of time after which they will be removed. Conversely, permanent brachytherapy means the seeds are never removed though they will eventually stop emitting radioactivity, usually within 3 to 12 months of implantation, depending on the dosage and type of radioactive material used in the treatment.

Brachytherapy is delivered as an outpatient procedure in a shielded room that can contain the radiation. It does not generally require a hospital stay except in the case of some high-dose varieties of this treatment. The seeds or rods are implanted by means of metal tubes or catheters. General or local anesthesia will be used to lessen discomfort. If the therapy is to be of the temporary variety, the applicator may be left in place until the seeds are removed.

When the procedure is complete, the patient may return home but may be advised to avoid interaction with pregnant women and small children, who are most prone to the effects of radiation. However, the amount of radiation released by a person who has undergone brachytherapy is fairly minimal.

Side Effects of Mesothelioma Radiation

Overall, radiation therapy carries far fewer side effects than chemotherapy though the two are often used together to treat mesothelioma cancer. The most common complaints from radiation patients include:

Many radiation patients find some relief from these side effects using alternative treatments such as massage, acupuncture, and aromatherapy.

Sources

http://www.cancer.gov/cancertopics/wtk/ebrt

http://www.cancer.org/.../radiation-therapy-what-it-is-external-beam-rad-therapy

http://www.americanbrachytherapy.org

http://www.cancer.org/.../understanding-radiation-therapy-internal-radiation-therapy

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Bruce Haffty, M.D.
Dr. Bruce Haffty is the Associate Director of the Cancer Institute of New Jersey. He specializes in cancer of the head and neck and studies the management of malignant mesothelioma using findings from his work in locating genetic markers in breast cancer.

Spencer McCachren, M.D.
Dr. Spencer McCachren is currently at the Thompson Oncology Group and is considered a specialist in the treatment of mesothelioma.

David Rice, M.D.
Dr. David Rice is an Associate Professor and Assistant Surgeon at The University of Texas M.D. Anderson Cancer Center where he serves as the director of the Minimally Invasive Surgery and Mesothelioma programs.

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