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Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Brief Summary

The purpose of this study is to determine the response rate and overall survival in patients that have been diagnosed with mesothelioma and will undergo chemotherapy, surgery and intensity modified radiation therapy (IMRT) as part of their standard of care.

Tracking Information
First Received DateNovember 20, 2015
Last Changed DateDecember 19, 2016
Start DateNovember 2015
Anticipated Primary Completion DateDecember 2018
Primary Outcome Measures

Survival status upon review of patients every 6 months [Time Frame: 2 years]

Secondary Outcome Measures

Progression free survival as evidenced by CT scan review [Time Frame: 2 years]

Descriptive Information
Study TypeObservational
  • Mesothelioma
  • Solitary Fibrous Tumor of the Pleura
Study Arms / Comparison Groups0 / 1
Detailed Description

The investigators will consent patients that have been diagnosed with mesothelioma and will undergo chemotherapy followed by surgery and then IMRT as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.

Recruitment Information
Recruitment StatusRecruiting
Anticipated Enrollment200
Ages18 Years - N/A
Accepts Healthy VolunteersNo
Contact Karlyn Pierson, RN
Phone: 507-293-0807
Eligibility Criteria

Inclusion Criteria:

- Subject provides informed consent

- Subject is >18 years of age

- Subject is deemed competent for making medical decisions

- Subject is scheduled to undergo chemotherapy followed by surgery and then IMRT

- Subject is a surgical candidate

- A negative pregnancy test is required in women of child-bearing potential, as standard of care.

Exclusion Criteria:

•Subject is <18 years old.

Administrative Information
Responsible Party,
SponsorMayo Clinic
Verification DateDecember 2016
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