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Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Brief Summary

The purpose of this study is to determine whether radiation therapy decreases tumor size and tumor spread. The investigators will consent subjects that have been diagnosed with mesothelioma and will undergo radiation therapy followed by surgical resection as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.

Tracking Information
First Received DateNovember 20, 2015
Last Changed DateFebruary 5, 2019
Start DateNovember 2015
Anticipated Primary Completion DateDecember 2020
Primary Outcome Measures

Survival status upon review of patient records every 6 months [Time Frame: 2 years]

Descriptive Information
Study TypeObservational
  • Mesothelioma
  • Solitary Fibrous Tumor of the Pleura
Recruitment Information
Recruitment StatusRecruiting
Anticipated Enrollment200
Ages18 Years - N/A
Accepts Healthy VolunteersNo
Contact Karlyn Pierson, RN
Phone: 507-293-0807
Eligibility Criteria

Inclusion Criteria:

- Subject provides informed consent

- Subject is >18 years of age

- Subject is deemed competent for making medical decisions

- Subject is scheduled to undergo radiation followed by extrapleural pneumonectomy.

- Subject is a surgical candidate

- A negative pregnancy test is required in women of child-bearing potential, as standard of care.

Exclusion Criteria:

- Subject is <18 years old.

Administrative Information
Responsible PartyPrincipal Investigator
SponsorMayo Clinic
Verification DateFebruary 2019
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