The purpose is to evaluate the activity and feasibility of a two drug regimen which is partly orally and partly intravenous in advanced pleural mesothelioma.
|First Received Date||January 3, 2006|
|Last Changed Date||September 17, 2009|
|Start Date||September 2004|
|Actual Primary Completion Date||September 2009|
|Primary Outcome Measures||
|Secondary Outcome Measures||
Chemotherapy with carboplatin i.v. day one in each cycle Vinorelbine i.v. day one, and orally day 8 in each cycle, repeat new cycle every 3 weeks. Total of 6 cycles.
Endpoint is response rate, secondary endpoints survival and toxicity.
|Ages||18 Years - 85 Years|
|Accepts Healthy Volunteers||No|
- Histologically verified malignant pleural Mesothelioma
- Age above 18 years
- Performance status 0-2
- No previous chemotherapy
- Normal renal, liver and bone marrow function
|Verification Date||September 2009|