Primary pericardial malignant mesothelioma and response to radiation therapy

Rare Tumors. 2010 Sep 30;2(3):e51.
Reardon KA, Reardon MA, Moskaluk CA, Grosh WW, Read PW.
Department of Radiation Oncology, University of Virginia.

We report a case of a primary pericardial malignant mesothelioma. A 59-year-old male presented with episodic chest pain and dyspnea on exertion. Cardiac magnetic resonance imaging revealed a large mass in the pericardium attached to the right ventricle. Partial resection of the mass was undertaken revealing malignant mesothelioma, byphasic type. The patient was treated with chemotherapy intermittently over a period of 3 years, but his disease continued to progress. The patient was then treated with definitive radiation therapy to 64 Gy to the primary tumor using a six field 3D conformal technique. The patient remains free of progressive disease 86 months from the time of diagnosis and 50 months from the completion of his radiotherapy.

Sources

PMID: 21139966 [PubMed - in process] PMCID: PMC2994533 Free PMC Article
http://www.ncbi.nlm.nih.gov/pubmed/21139966?dopt=AbstractPlus