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Heated Intraoperative Intraperitoneal Chemotherapy Developed by Renowned Surgeon
Dr. Paul Sugarbaker, renowned oncologic surgeon specializing in mesothelioma at the Washington Cancer Institute, developed a leading-edge surgical procedure to treat mesothelioma called heated intraoperative intraperitoneal chemotherapy. In this procedure, as much of the tumor as possible is first removed by the surgeon. Following the removal of the tumor, a chemotherapy agent heated to between 40°C and 48°C is administered into the abdomen. The fluid is perfused for anywhere between one and two hours and then it is drained.
High concentrations of selected drugs can be administered into the abdominal and pelvic surfaces using this technique. The other benefit associated with using this technique to treat peritoneal mesothelioma is that the heated chemotherapy treatment increases the level to which the drugs can penetrate the tissues and damages malignant cells more than normal ones.